Efficient synthesis of benzophenone derivatives in Lewis acid ionic liquids

摘要

Benzophenone and its derivatives were prepared via Friedel-Crafts acylation reactions using ionic liquids (ILs) of BmimCl-FeCl3,BmimCl-AlCl3 and BmimCl-ZnCl2 as dual catalyst-solvent.Among them,BmimCl-FeCl3 showed much higher catalytic activity than that observed for the other two ILs,and in conventional organic solvents.In these reaction systems,good to excellent yields (up to 97%) of acylation products were obtained in a short reaction time.This method features high yield,a simple product isolation procedure,ILs reusability and reduced waste discharge,thus rendering this catalytic system both efficient and environmentally friendly.