On the Laser-induced Heat Profile for Skin-Thermolysis by Using an Egg White Protein Simulation Model

摘要

Nowadays, the technology of lasers in the dermatological profession has developed and provided an effective result to patients by using fractional 1550 nm lasers. The depth of skin and quantity of treatment can be controlled step by step. Patients may not have side effects after having treatment and can continue a regular lifestyle. This is because the laser beam is divided in a great number of small beams for each treatment area. The trace of injury cannot be detected by the eye. Controlling the energy of the laser for getting the most suitable depth and trace of injury for each skin disease is very important. Testing the right amount of laser energy for a biopsy from volunteer patients is difficult in terms of data analysis. The sample size could be very limited, which leads to an insignificant statistical result problem. This is because of the ethical problem with regards to conducting research on humans. Therefore, the development of lasers in dermatological profession has been slower than in other industrial and science fields. Inventing a substitute material for experiment with a fractional 1550 nm laser is very important. The substitute material has to have a physical reaction similar to human skin. This will benefit the study of the microscopic heating expansion in human skin before operating with the laser treatment for patients. This research presents natural egg white as a substitute material. Egg white has a mechanism to absorb the energy from a fractional 1550 nm laser, which is similar to mechanism in human skin. Analysis of the pattern of laser beam in egg white by microscope from liquid egg white is fast. This could be done immediately after conducting the experiment. The experiment time and expenses of egg white experiment are 1 and 0.33% comparing to the experiment with volunteer patients.