POSS supported diarylprolinol silyl ether as an efficient and recyclable organocatalyst for asymmetric Michael addition reactions

摘要

The POSS supported (S)-alpha,alpha-diphenylprolinol trimethylsilyl ether catalyst was synthesized and applied in the asymmetric Michael addition reactions of aldehydes and arylnitroalkenes, providing the products in good yields with excellent enantioselectivities and good diastereoselectivities. The POSS supported catalyst can be readily recycled and reused for further transformations at least eight cycles without observing significant decrease in yield and stereoselectivity. (C) 2015 Elsevier B.V. All rights reserved.