Synthesis of Quinazoline-2,4(1H,3H)-Diones from Carbon dioxide and 2-Aminobenzonitriles Using MgO/ZrO2 as a Solid Base Catalyst

摘要

The synthesis of quinazoline-2,4(1H,3H)-di-ones from carbon dioxide and 2-aminobenzonitriles using MgO/ZrO2 as a novel and efficient heterogeneous base catalyst is reported. The synthesized MgO/ZrO2 catalyst was characterized by XRD, FTIR and its basic properties were measured using CO2 temperature programed desorp-tion analysis. The effects of various reaction parameters were investigated in detail. A wide variety of aromatic aminobenzonitriles and five member N-heterocyclic car-bonitriles were synthesized using this protocol.