A role of 1,25(OH)(2)D-3 supplementation in rats with nonalcoholic steatohepatitis induced by choline-deficient diet

摘要

Background and aims: It has been reported that 1,25(OH)(2)D-3 (1,25-VD3) ameliorates the progression of nonalcoholic steatohepatitis (NASH). However, it is unclear whether 1,25-VD3 plays a role in NASH induced by a choline-deficient (CD) diet. In this study, we investigated the roles of 1,25-VD3 in the development and progression of NASH in rats induced by a CD diet.