Comparison of the effects of milk components and calcium source on calcium bioavailability in growing male rats.

摘要

Six-week-old male Sprague-Dawley rats were divided into 4 groups and fed the following diets for 46 days: Milk components (MC)+CaCO3, CaCO3, MC+WheyCa and WheyCa. Ca bioavailability was defined by apparent Ca absorption rate and bone mineral density(BMD). Two-way ANOVA was used to estimate the effects of milk components and Ca source on Ca availability. The apparent Ca absorption rate was estimated at 7 and 12 weeks of age. The type of dietary Ca source did not affect Ca absorption rate in eitherperiod. However, the milk components significantly increased apparent Ca absorption rate at 7 weeks of age, and tended to increase apparent Ca absorption rate at 12 weeks of age (P=0.09). Moreover, the milk components increased the apparent Mg absorptionrate in both periods. The type of dietary Ca source did not affect the BMD of the femur or lumbar vertebrae (L3-L5). However, the milk components diet increased the BMD of femur and L3-L5. These data indicate that the administration of milk components is more effective for the enhancement of Ca availability than the chemical form of Ca in growing rats.