The biodistribution of maltotriose modified poly(propylene imine) (PPI) dendrimers conjugated with fluorescein—proofs of crossing blood-brain-barrier

摘要

Oligosaccharide-modified poly(propylene imine) dendrimers are promising candidates as drug carriers and as anti-prion agents. Here, we report the biodistribution of maltotriose-modifled 4th generation poly(propylene imine) (PPI) dendrimers and their ability to cross the blood-brain-barrier that is important if these glycodendrimers are considered as potential therapeutic agents in the central nervous system (CNS).