Dynamics of Cognitive Anomalies in Patients with First Episodes of Juvenile Endogenous Psychosis

摘要

The therapeutic dynamics of neuropsychological and neurophysiological markers of impairments to cog-nitive functions were studied in groups of patients with first episodes of juvenile endogenous psychosis(90 patients). At the initial stage of remission, subjects were found to show improvements in processesassociated with voluntary regulation of cognitive functions (due to the activity of extensive networks ofcortical and subcortical structures), while more automatic processes (associated mainly with the temporalareas of the brain) remained abnormal. Changes in neurocognitive anomalies during the onset of remissionwere also identified in groups of patients in whom episodes had different syndromal structures – catatonic,hallucinatory-delusional, and affective-delusional.