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Adolescent oxycodone self administration alters subsequent oxycodone-induced conditioned place preference and antinociceptive effect in C57BL/6J mice in adulthood

机译:青春期羟考酮的自我给药改变了成年期C57BL / 6J小鼠中羟考酮诱导的条件性位置偏爱和抗伤害感受的作用

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摘要

Adolescent and young adult abuse of short-acting MOP-r agonists such as oxycodone is a pressing public health issue. Few preclinical studies have examined how adolescent exposure to oxycodone impacts its effects in the transition to adulthood.
机译:青少年和年轻人滥用短效MOP-r激动剂(例如羟考酮)是一个紧迫的公共卫生问题。很少有临床前研究检查过青春期羟考酮的暴露如何影响其在成年期过渡中的作用。

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