Addictive Drugs and Stress Trigger a Common Change at VTA Synapses.

摘要

In this issue of Neuron, Saal et al. find that exposure to any of five addictive drugs or exposure to a brief stressor produces a shared cellular modification of excitatory synapses in the ventral tegmental area (VTA). This common response may represent a starting point for dissecting early changes that underlie addiction.