174th ENMC international workshop: Applying pre-implantation genetic diagnosis to mtDNA diseases: implications of scientific advances 19-21 March 2010, Naarden, The Netherlands.

摘要

Ten years and 100 workshops after the first ENMC International Workshop on genetic management for mitochondrial DNA (mtDNA) disorders [4], 18 participants, including clinicians, basic scientists, an ethicist and a patient representative from 9 countries gathered on 19-21 March, 2010, in Naarden, The Netherlands. This was in order to (1) provide a consensus statement on the role and application of pre-implantation genetic diagnosis (PGD) to mtDNA disease and (2) review new data on the biology of mtDNA in the germline and assess its implications for genetic management.