TERATOGENIC EFFECT OF SODIUM METABISULPHITE IN THE EMBRYOGENESIS OF Gallus gallus domesticus

摘要

The pinnacle of advances in food processing offered tremendous advantage in thepreservation of foods with the aid of food additives. One of the commonly used foodpreservatives is the derivatives of sulfite, Sodium Metabisulfite (SMB). In this study, theteratogenic effect of SMB are evaluated using the Chicken Embryo Test. The 2.5, 10, and40 ppm of SMB were administered into chicken eggs using the standard procedure. The40 samples of eggs were placed in a commercial incubator. After 5 days incubationperiod, the eggs were examined for specific developmental anomalies. The resultsshowed that malformations and deformities were observed in chicken embryo and therewere even suppressions of growth and development especially in the 40 ppmconcentration. Thus, the study has shown that SMB probably triggers teratogenic effectson the developmental stages in chicken embryo.