Evaluation of anti-inflammatory activity of the plant extract Smithia Sensitiva

摘要

To evaluate the anti-inflammatory property of the whole plant of Smithia sensitiva. Smithia sensitiva belonging to the family Fabaceae is a plant used as an anti inflammatory and anti oxidant drug by tribal peoples in kerala. Smithia sensitiva is a low growing annual herb 30-90cm long and it is distributed widely in Hilly areas. The whole plant is traditionally used as Refrigerant, Galactogogue and as lotion in headaches. The present study aimed at the evaluation of the anti-inflammatory activity of the methanolic extract of Smithia sensitiva (MESS) by both in vitro and in vivo method. In vitro method was estimated by bovine serum albumin denaturation (BSA) method and in vivo method was estimated by Cotton pellet-induced granuloma method. Both the methods showed significant antiinflammatory property of the methanolic extract. The MESS at a concentration of 400mu;g/ml showed potent activity on comparing with the standard drug.