A microwave-assisted synthesis of phenanthroperylene quinones as exemplified with hypericin

摘要

The synthesis of hypericin,one of the most important phenanthoperylene quinones used in photo-dynamic therapy,could be highly improved by using either a microwave-assisted dimerization of emodin-anthrone,or a mixed dimerization of emodinanthrone with emodin in the presence of potassium t-butoxide as the key-step.