Sodium Bisulfite as an Efficient and Inexpensive Catalyst for the One-pot Synthesis of 2,4,5-Triaryl-1H-imidazoles from Benzil or Benzoin and Aromatic Aldehydes

摘要

2,4,5-Triaryl-1H-imidazoles were efficiently synthesized from benzoin or benzil, ammonium acetate, and aromatic or heteroaromatic aldehydes in the presence of sodium bisulfite as catalyst. The present protocol offers significant improvements for the synthesis of 2,4,5-triaryl-1H-imidazoles with regard to yield of products, simplicity in operation, and cheap catalyst.