Lingual epilepsia partialis continua as the presenting manifestation of herpes simplex encephalitis: Uncommon presentation of a common disease

摘要

Copper is a very important trace element. It is required for basic cell functioning and is a cofactor in a number vital enzymes necessary for the nervous system. The first case of copper deficiency-related myelopathy in humans was reported in 2001. Clinically, a presentation similar to B12 deficiency myelopathy has been described, with neurological examination findings suggestive of pyramidal and posterior column abnormalities. Commonly, spinal cord magnetic resonance imaging (MRI) studies display abnormal T2 signals in the posterior cord and EMG studies demonstrate an axonal peripheral neuropathy. We report a case of acquired demyelinating neuropathy due to copper deficiency.