Therapy: Intralesional nicardipine: another calcium channel blocker shown to be effective in patients with Peyronie's disease.

摘要

The search for an effective nonsurgical treatment for patients with Peyronie's disease (PD), a condition characterized by the development of fibromatosis in the tunica albuginea resulting in pain and abnormal penile curvature, has yet to yield an approach with satisfactory efficacy. Among the many treatments to be tested in these patients, such as shock wave therapy, radiation therapy, an array of oral agents, and intralesional injection of steroids or interferons-all of which have shown poor efficacy-intralesional administration of the non-dihydropyridine calcium channel blocker verapamil has had reasonably promising results.