Prophylactic effect of antibiotic lock solution on bacteremia related to use of uncuffed hemodialysis catheters

摘要

In order to minimize the risk of hemodialysis catheter-related bacteremia (CRB), the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (KDOQI) guidelines advocate use of tunneled cuffed catheters for temporary vascular access in individuals lacking a mature arteriovenous access. Uncuffed catheters are nevertheless widely used for reasons of cost and convenience. OBJECTIVE To determine whether use of an antibiotic lock solution can reduce the risk of CRB in patients with uncuffed hemodialysis catheters.