Is there a role for oral rapamycin in restenosis prevention after bare-metal stent implantation?

摘要

Despite the success of drug-eluting stents in reducing the rate of restenosis following angio-plasty, their long-term safety has not yet been proven. There is a need, therefore, for alternative strategies to prevent in-stent restenosis after intervention. OBJECTIVE To find out whether short-term oral rapamycin therapy can lower the restenosis rate in patients who have received bare-metal stents (BMSs).