The most versatile of all reactive intermediates?

摘要

The iron( II)- and 2- oxoglutarate- dependent oxygenases catalyze varied oxidative reactions. Spectroscopic analyses on the catalytic cycle of the chlorinating enzyme CytC3 reveal the presence of chloride - iron( IV) - oxo complexes, expanding the scope of chemistry known to be catalyzed by non- heme iron- oxo species.