Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in early stage squamous cell carcinoma of the lung

摘要

Lung cancer is the leading cause of cancer death in the United States and other countries, including Japan.~(1) Despite the potential benefits of surgical resection, patients with the same pathologic stage of disease display marked variability in the possibility of recurrence and the survival. Moreover, the outcome after treatment has been very dismal in many cases. At present, no predictive factors have been demonstrated in patients with stage I non-small-cell lung cancer (NSCLC) who are at increased risk of disease recurrence#