CYTOSKELETAL PROTEINS AND STEROIDOGENESIS IN GRANULOSA AND THECA CELLS OF PORCINE FOLLICLE

摘要

The participation of microtubules and microfilaments in steroidogenesis of both theca (T) and granulosa (G) cells in mono- and coculture was assayed by monitoring the effect of colchicine (Col) and cytochalasin B (Cyt B) on estradiol (E2) secretion during 24 hours of culture. In coculture Col and Cyt stimulated E2 secretion, which suggests that both microtubules and microfilamentes are involved in E2 secretion.