首页> 外文期刊>Netherlands Journal of Zoology >RECEPTORS OF BIOGENIC AMINES IN MUSCLE MEMBRANES OF MOLLUSCS
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RECEPTORS OF BIOGENIC AMINES IN MUSCLE MEMBRANES OF MOLLUSCS

机译:软体动物肌肉膜中生物胺的受体

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In a number of molluscs belonging to different groups, serotonin and beta-adrenergic agonists have a stimulatory effect on the sarcolemmal adenylyl cyclase (AC) activity, which is potentiated by guanine nucleotides. Catecholamines (isoprotenerol > adrenaline > noradrenaline) inhibit AC activity in Anodonta cygnea sarcolemma. In muscle membranes of Anodonta, Mizuhopectin and Spisula, a serotonin receptor (5-HTR) and a beta-adrenoreceptor (beta-AR) were identified. Guanine nucleotides lowered the affinities of 5-HTR and beta-AR to agonists.
机译:在许多属于不同族的软体动物中,5-羟色胺和β-肾上腺素能激动剂对肌膜腺苷酸环化酶(AC)的活性有刺激作用,该活性被鸟嘌呤核苷酸增强。儿茶酚胺(异丙肾上腺素>肾上腺素>去甲肾上腺素)抑制Anodonta cygnea sarcolemma中的AC活性。在Anodonta,Mizuhopectin和Spisula的肌膜中,鉴定出了血清素受体(5-HTR)和β-肾上腺素能受体(beta-AR)。鸟嘌呤核苷酸降低了5-HTR和β-AR与激动剂的亲和力。

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