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New triterpene glycosides from Camptosorus sibiricus

机译:喜树(Camptosorus sibiricus)的新三萜糖苷

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摘要

Two new cycloartane glycosides were isolated from the whole herbs of Camptosorus sibiricus Rupr. By means of chemical and spectroscopic methods (1D and 2D NMR, HRMS, ESI-MS), the structures were established as (24R)-3β,7β,24,25,30-pentahydroxycycloartane-30-O-coumaroyl-3-O- β-D-glucopyranosyl-24-O-β-D-glucopyranosyl-(1→6) -β-D-glucopyranoside (1) and (24R)-3β,7β,24,25,30-pentahydroxy-1- ene-cycloartane 24-O-β-D-glucopyranoside (2). The two new compounds were inactive in vitro against A375-S2 and Hela human tumor cell lines using the MTT method.
机译:从喜树(Camptosorus sibiricus Rupr)的整个草药中分离出两种新的环烷烷苷。通过化学和光谱方法(1D和2D NMR,HRMS,ESI-MS),将结构确定为(24R)-3β,7β,24,25,30-五羟基环烷30-30-O-香豆酰基-3-O -β-D-吡喃葡萄糖基-24-O-β-D-吡喃葡萄糖基-(1→6)-β-D-吡喃葡萄糖苷(1)和(24R)-3β,7β,24,25,30-五羟基-1-烯-环烷烃24-O-β-D-吡喃葡萄糖苷(2)。使用MTT方法,这两种新化合物在体外对A375-S2和Hela人肿瘤细胞系无活性。

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