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Anti-proliferative Constituents from Selaginella moellendorffii

机译:卷柏卷柏的抗增殖成分

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摘要

Two new compounds, (3R)-5,6,7-trihydroxy-3-isopropyl-3-methylisochroman-1-one (1) and rhamnocitrin-3-O-beta-glucopyranosyl-4'-O-beta-galactosyl-(1 -> 3)-glucopyranoside (2), were isolated from the whole plants of Selaginella moellendorffii Hieron. Their structures were determined by spectroscopic methods. Additionally, compound 1 could inhibit the proliferation of HT29 cells through inducing cell apoptosis.
机译:两种新化合物(3R)-5,6,7-三羟基-3-异丙基-3-甲基异苯并二氢吡喃-1-酮(1)和鼠李糖胞苷-3-O-β-吡喃葡萄糖基-4'-O-β-半乳糖基- (1→3)-吡喃葡萄糖苷(2)从卷柏卷柏的整个植物中分离出来。通过光谱法确定它们的结构。另外,化合物1可以通过诱导细胞凋亡来抑制HT29细胞的增殖。

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