ATLANTA- At the annual Conference on Retroviruses and Opportunistic Infections (CROI) that took place almost exactly a year ago, researchers reported the first clinical evidence that the drug vorinostat could shock HIV out of its hiding places in patients, potentially allowing the once-dormant virus to be detected by the immune system and thereby cleared from the body. The release of the vorinostat findings hinted at a future in which HIV-infected individuals would not have to stay on lifelong drug therapy, as currently recommended. Amidst the buzz surrounding the results, there was just one word on everyone's lips: cure (see Nat. Med. 18,473,2012).
展开▼
