Using length of Barrett oesophagus to determine risk of progression to high-grade dysplasia and adenocarcinoma

摘要

"Previous reports in small numbers of patients with Barrett oesophagus have suggested a relationship between the length of Barrett oesophagus and cancer risk," explains Prateek Sharma (University of Kansas School of Medicine, USA). As the relationship was not consistent in these small studies, Sharma and colleagues investigated the association in a large cohort of patients.The cohort included 1,175 patients with Barrett oesophagus but no dysplasia who were followed up for at least 1 year at five different tertiary care centres in the USA (participants of the Barrett Esophagus Study).