Proteomics: Biomarkers on a nanoscale

摘要

The quantitative assessment of protein expression and phosphoryla-tion in tumours from animal models and human patients could provide functional insight into disease progression and therapeutic responses. However, proteomic approaches are limited by the requirement for large samples and numerous processing procedures prior to analysis. Now, Dean Felsher and colleagues have developed the nanofluidic proteomic assay (NIA), which could reinvigorate the use of proteomics in research, drug development and the clinic.