Celebrating the first 10 years of Nature Reviews Cardiology

摘要

The past 10 years have seen great advances in cardiovascular medicine. These changes are summarized in a series of Decade in Review articles that were specially commissioned from keysopinion leaders in cardiology. Antithrombotic therapy has been revolutionized by the development of direct-acting oral anticoagulant drugs and novel antiplatelet agents. These new classes of compound have particularly benefitted patients with acute coronary syndrome or venous thromboembolism (as reviewed by Frans Van de Werf and Mark Creager, respectively), and those with atrial fibrillation, who are at risk of stroke (as highlighted by Stanley Nattel). John Kastelein describes the major advances in lipid-lowering therapy with statins for patients with dyslipidaemia, and anticipates the approval of monoclonal antibodies against PCSK9, which are expected to provide further benefit for these patients.