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Nanosized corners for trapping and detecting magnetic nanoparticles

机译:用于捕获和检测磁性纳米粒子的纳米角

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摘要

We present a device concept based on controlled micromagnetic configurations in a corner-shaped permalloy nanostructure terminated with two circular disks, specifically designed for the capture and detection of a small number of magnetic beads in suspension. A transverse head-to-head domain wall (TDW) placed at the corner of the structure plays the role of an attracting pole for magnetic beads. The TDWis annihilated in the terminating disks by applying an appropriate magnetic field, whose value is affected by the presence of beads chemically bound to the surface. In the case where the beads are not chemically bound to the surface, the annihilation of the TDW causes their release into the suspension. The variation of the voltage drop across the corner, due to the anisotropic magnetoresistance (AMR) while sweeping the magnetic field, is used to detect the presence of a chemically bound bead. The device response has been characterized by using both synthetic antiferromagnetic nanoparticles (disks of 70 nm diameter and 20 nm height) and magnetic nanobeads, for different thicknesses of the protective capping layer. We demonstrate the detection down to a single nanoparticle, therefore the device holds the potential for the localization and detection of small numbers of molecules immobilized on the particle’s functionalized surface.
机译:我们提出了一种设备概念,该设备概念基于以两个圆盘终止的角形坡莫合金纳米结构中的受控微磁配置,特别设计用于捕获和检测悬浮液中的少量磁珠。放置在结构角处的横向头对头磁畴壁(TDW)充当磁珠的吸引极。 TDWi通过施加适当的磁场而消失在端接盘中,该磁场的值受化学键合到表面的磁珠的存在影响。在珠未化学键合到表面的情况下,TDW的an灭会导致其释放到悬浮液中。由于在扫描磁场时的各向异性磁阻(AMR),拐角处的电压降变化用于检测化学结合的磁珠的存在。通过使用合成反铁磁纳米粒子(直径为70 nm的圆盘和高度为20 nm的圆盘)和磁性纳米珠来表征设备响应,以用于不同厚度的保护性覆盖层。我们演示了可检测到单个纳米颗粒的检测方法,因此该设备具有定位和检测固定在颗粒功能化表面上的少量分子的潜力。

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