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DNA Methyltransferases and Structural-Functional Specificity of Eukaryotic DNA Modification

机译:DNA甲基转移酶和真核DNA修饰的结构功能特异性。

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摘要

Properties of the main families of mammalian,plant,and fungal DNA methyltransferases are considered.Structural-functional specificity of eukaryotic genome sequences methylated by DNA methyltransferases is characterized.The total methylation of cytosine in DNA sequences is described,as well as its relation with RNA interference.Mechanisms of regulation of expression and modulation of DNA methyltransferase activity in the eukaryotic cell are discussed.
机译:考虑了哺乳动物,植物和真菌的主要DNA甲基转移酶的家族特性。表征了被DNA甲基转移酶甲基化的真核基因组序列的结构功能特异性。描述了DNA序列中胞嘧啶的总甲基化及其与RNA的关系讨论了在真核细胞中调节表达和调节DNA甲基转移酶活性的机制。

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