Twenty-six week or longer intracerebroventricular (ICV) infusion study of BMN 250 administered once every 2 weeks in a canine model of mucopolysaccharidosis type IIIB (MPS MB)

Ellinwood N. Matthew; Johnson Bethann N.; Jens Jackie K.; Snella Elizabeth M.; Ware Wendy A.; Hostetter Shannon; Ben-Shlomo Gil; Jeffery Nicholas; Safayi Sina; Millman Suzanne; Parsons Rebecca; Vuillemenot Brian R.; Butt Mark T.; Cooper Jonathan; Nestrasil Igor; Wendt Daniel; Kennedy Derek; Grover Anita; Melton Andrew; Cherukuri Anu; Wait Jill C. M.; Pinkstaff Jason K.

首页> 外文期刊>Molecular genetics and metabolism >Twenty-six week or longer intracerebroventricular (ICV) infusion study of BMN 250 administered once every 2 weeks in a canine model of mucopolysaccharidosis type IIIB (MPS MB)

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Twenty-six week or longer intracerebroventricular (ICV) infusion study of BMN 250 administered once every 2 weeks in a canine model of mucopolysaccharidosis type IIIB (MPS MB)

机译：BMN 250的26周或更长时间的脑室内（ICV）输注研究，每2周一次在犬黏多糖贮积症IIIB型（MPS MB）模型中进行

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《Molecular genetics and metabolism 》 |2016年第2期| 共1页
作者
Ellinwood N. Matthew; Johnson Bethann N.; Jens Jackie K.; Snella Elizabeth M.; Ware Wendy A.; Hostetter Shannon; Ben-Shlomo Gil; Jeffery Nicholas; Safayi Sina; Millman Suzanne; Parsons Rebecca; Vuillemenot Brian R.; Butt Mark T.; Cooper Jonathan; Nestrasil Igor; Wendt Daniel; Kennedy Derek; Grover Anita; Melton Andrew; Cherukuri Anu; Wait Jill C. M.; Pinkstaff Jason K.;
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中图分类内分泌腺疾病及代谢病 ;
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1. Twenty-six week or longer intracerebroventricular (ICV) infusion study of BMN 250 administered once every 2 weeks in a canine model of mucopolysaccharidosis type IIIB (MPS MB) [J] . Ellinwood N. Matthew, Johnson Bethann N., Jens Jackie K., Molecular genetics and metabolism . 2016 ,第2期

机译：BMN 250的26周或更长时间的脑室内（ICV）输注研究，每2周一次在犬黏多糖贮积症IIIB型（MPS MB）模型中进行
2. Preliminary findings of a twenty-six week or longer intracerebroventricular infusion study of BMN 250 administered once every 2 weeks in a canine model of mucopolysaccharidosis type IIIB [J] . Ellinwood N. Matthew, Valentine Bethann, Hess Andrew S., Molecular genetics and metabolism . 2017 ,第1a2期

机译：26周或较长的颅内腔内输注研究BMN 250的初步发现每2周给药一次粘多型型肉瘤型IIIB的犬模型
3. Pharmacology of BMN 250 administered via intracerebroventricular infusion once every 2 weeks for twenty-six weeks or longer in a canine model of mucopolysaccharidosis type IIIB [J] . Ellinwood N. Matthew, Valentine Bethann, Hess Andrew S., Molecular genetics and metabolism . 2018 ,第2期

机译：BMN 250的药理学通过颅内腔内输注一次每2周施用26周或在粘性多型型IIIB的犬模型中或更长时间
4. STUDYING THE IMPACT OF LAND USE/COVER CHANGES ON THE WATER QUALITY OF WEEKS BAY, AL: MODEL vs. REGRESSION [C] . Harsh Vardhan Singh, Latif Kalin, Graeme Lockaby . 2009

机译：研究土地利用/覆盖变化对周湾水质的影响：模型与回归
5. Mucopolysaccharidosis type IIIB and GalNAc Transferase double knockout mice and additional studies in gene therapy and animal models to assess pathogenesis and therapy. [D] . Mohammed, Eman. 2012

机译：IIIB型粘多糖贮积病和GalNAc转移酶双敲除小鼠以及基因治疗和动物模型的其他研究，以评估发病机理和治疗方法。
6. An open-label dose-escalation safety and pharmacokinetics phase I study of ombrabulin a vascular disrupting agent administered as a 30-min intravenous infusion every 3 weeks in Japanese patients with advanced solid tumors [O] . H. Murakami, T. Kurata, Y. Onozawa, -1

机译：一项开放性剂量递增安全性和药代动力学I期研究ombrabulin（一种血管破裂剂）每3周对日本晚期实体瘤患者进行30分钟静脉输注
7. Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type B [O] . Anita Grover, Danielle Crippen-Harmon, Lacey Nave, 2020

机译：用于BMN 250的CNS细胞生物分布静脉内和脑室间诊断途径的翻译研究，酶替代治疗Sanfilippo型B.
8. NIEHS Technical Report on the 13-Week Toxicity Study of 3'-Azido-3'-deoxythymidine (AZT) and Isoniazid Combinations (CAS Nos. 30516-87-1 and 54-85-3) Administered by Gavage to B6C3F(sub 1) Mice. NIEHS AIDS Therapeutics Toxicity Report Number 8 [R] . 2002

机译：NIEHs关于3'-叠氮基-3'-脱氧胸苷（aZT）和异烟肼组合（Cas号30516-87-1和54-85-3）的13周毒性研究的技术报告通过管饲给予B6C3F（sub 1））老鼠。 NIEHs艾滋病治疗毒性报告第8号

Twenty-six week or longer intracerebroventricular (ICV) infusion study of BMN 250 administered once every 2 weeks in a canine model of mucopolysaccharidosis type IIIB (MPS MB)

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