Functional Properties of 50% Methanol Extracts from Different Parts of Acanthopanax sessiliflorus

摘要

This study was carried out in order to investigate the functional properties of 50% methanol extracts from four parts (root, stem, leaf and fruit) of Acanthopanax sessiliflorus by means of measuring the contents of eleutheroside B, E, and total polyphenols as well as determining electron donating ability (EDA), nitrite scavenging ability (NSA), and anticancer activity. The highest contents of eleutheroside B and E were found in the fruit (538.99 ug/g) and the stem (556.00 mu g/g). The root extract demonstrated the highest polyphenol content (2.97 mg/g). EDA of the stem and root extracts were 90.21% and 85.71%. All of the extracts showed 81.5-93.0% of NSA at pH 1.2. In addition all extracts indicated no cytotoxicity to normal cell line (DC2.4). The root extract had a 23% inhibitory effect against the stomach cancer cell line (SNU-719). These results revealed that 50% methanol extracts from A. sessiliflorus can be used as a potential resource of nutraceuticals.