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首页> 外文期刊>Knee surgery, sports traumatology, arthroscopy: official journal of the ESSKA >Expression of insulin-like growth factor type 1 receptor and myosin heavy chain in rabbit's rotator cuff muscle after injection of adipose-derived stem cell.
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Expression of insulin-like growth factor type 1 receptor and myosin heavy chain in rabbit's rotator cuff muscle after injection of adipose-derived stem cell.

机译:注射脂肪来源的干细胞后,胰岛素样生长因子1型受体和肌球蛋白重链在兔肩袖肌肉中的表达。

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摘要

The injection of ADMSCs resulted in high expression of IGF-1R and MyHC in subacute rotator cuff tear and repaired model in rabbit compared to control side. Therefore, the injected ADMSCs may assist in regeneration of the rotator cuff muscle by way of insulin-like growth factor 1 (IGF-1) signalling pathway. This result may suggest another solution to facilitate the recovery of rotator cuff muscle and to improve the result of rotator cuff repair by ADMSC injection via IGF-1 pathway, which is one of the potent anabolic pathways.
机译:与对照组相比,ADMSCs的注射导致兔亚急性肩袖撕裂和修复模型中IGF-1R和MyHC的高表达。因此,注射的ADMSC可通过胰岛素样生长因子1(IGF-1)信号传导途径协助肩袖肌的再生。该结果可能提示另一种解决方案,该解决方案有助于通过经由IGF-1途径的ADMSC注射而促进肩袖肌的恢复,并改善肩袖修复的结果,这是有效的合成代谢途径之一。

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