Stem cell transplantation compared with melphalan plus dexamethasone in the treatment of immunoglobulin light-chain amyloidosis

Gertz Morie A.; Lacy Martha Q.; Dispenzieri Angela; Buadi Francis K.; Dingli David; Hayman Suzanne R.; Kumar Shaji K.; Leung Nelson; Lust John; Rajkumar S. Vincent; Russell Stephen J.; Suman Vera J.; Le-Rademacher Jennifer G.; Hogan William J.

首页> 外文期刊>Cancer: A Journal of the American Cancer Society >Stem cell transplantation compared with melphalan plus dexamethasone in the treatment of immunoglobulin light-chain amyloidosis

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Stem cell transplantation compared with melphalan plus dexamethasone in the treatment of immunoglobulin light-chain amyloidosis

机译：干细胞移植与美法仑加地塞米松治疗免疫球蛋白轻链淀粉样变性病的比较

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BACKGROUNDAutologous stem cell transplantation (SCT) is a common management strategy for select patients with immunoglobulin light-chain amyloidosis, but no trials have documented improved overall survival.

机译：背景自体干细胞移植（SCT）是某些免疫球蛋白轻链淀粉样变性患者的常用治疗策略，但尚无试验证明总生存期得到改善。

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《Cancer: A Journal of the American Cancer Society 》 |2016年第14期| 共9页
作者
Gertz Morie A.; Lacy Martha Q.; Dispenzieri Angela; Buadi Francis K.; Dingli David; Hayman Suzanne R.; Kumar Shaji K.; Leung Nelson; Lust John; Rajkumar S. Vincent; Russell Stephen J.; Suman Vera J.; Le-Rademacher Jennifer G.; Hogan William J.;
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正文语种 eng
中图分类肿瘤学 ;
关键词
dexamethasone; immunoglobulin light chains; light-chain amyloidosis; melphalan; stem cell transplantation;

机译：地塞米松;免疫球蛋白轻链;轻链淀粉样变性;美法仑;干细胞移植;

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专利

1. Stem cell transplantation compared with melphalan plus dexamethasone in the treatment of immunoglobulin light-chain amyloidosis [J] . Gertz Morie A., Lacy Martha Q., Dispenzieri Angela, Cancer: A Journal of the American Cancer Society . 2016 ,第14期

机译：干细胞移植与美法仑加地塞米松治疗免疫球蛋白轻链淀粉样变性病的比较
2. Predictors of survival in patients with systemic light-chain amyloidosis and cardiac involvement initially ineligible for stem cell transplantation and treated with oral melphalan and dexamethasone. [J] . Lebovic D, Hoffman J, Levine BM, British Journal of Haematology . 2008 ,第3期

机译：系统性轻链淀粉样变性和心脏受累患者的生存预测指标最初不适合干细胞移植，并经口服美法仑和地塞米松治疗。
3. Cyclophosphamide plus Thalidomide plus Dexamethasone Versus Melphalan plus Dexamethasone for the Treatment of Amyloid Light-chain Amyloidosis With Kidney Involvement: A Retrospective Study in Chinese Patients [J] . Liu Baojian, Wang Yan, Bai Ming, Clinical therapeutics . 2019 ,第6期

机译：环磷酰胺加沙利度胺加上地塞米松对丁二醇加上的氨苄基甲基芹甲烷，用于治疗淀粉样蛋白轻链淀粉样蛋白病，肾脏受累：中国患者的回顾性研究
4. OVEREXPRESSION OF CALRETICULIN IN CLONAL AL PLASMA CELLS IS ASSOCIATED WITH RESPONSE TO MELPHALAN AND AUTOLOGOUS STEM CELL TRANSPLANT IN SYSTEMIC LIGHT-CHAIN (AL) AMYLOIDOSIS [C] . J Teruya-Feldstein, P.. Zhou, A B. Olshen, International Symposium on Amyloidosis . 2008

机译：克隆Al血浆细胞中CalreteteLin的过度表达与蛋白酶轻链（Al）淀粉样蛋白病中的莫酚和自体干细胞移植的反应有关
5. Evaluation of the effectiveness of Sertoli cells to suppress immune responses for the potential use as a safer alternative to systemic immune suppression in clinical islet transplantation for the treatment of type 1 diabetes [D] . Lord, Sarah Jean 2005

机译：评价血液细胞抑制免疫应答的潜在用途的潜在用途，作为临床胰岛移植在临床胰腺移植中的含有型1型糖尿病的替代品
6. Stem Cell Transplantation Compared With Melphalan Plus Dexamethasone in the Treatment of Immunoglobulin Light Chain Amyloidosis [O] . Morie A. Gertz, Martha Q. Lacy, Angela Dispenzieri, -1

机译：干细胞移植与美法仑加地塞米松治疗免疫球蛋白轻链淀粉样变性病的比较
7. High-Dose Melphalan and Stem Cell Transplantation in Patients on Dialysis Due to Immunoglobulin Light-Chain Amyloidosis and Monoclonal Immunoglobulin Deposition Disease [O] . Felipe Batalini, Laura Econimo, Karen Quillen, 2018

机译：透析患者的高剂量蛋白酶和干细胞移植因免疫球蛋白轻链淀粉样蛋白病和单克隆免疫球蛋白沉积疾病

Stem cell transplantation compared with melphalan plus dexamethasone in the treatment of immunoglobulin light-chain amyloidosis

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