Yeast unravels epigenetic apoptosis control: Deadly chat within a histone tail

摘要

An important paper by David Allis and colleagues (Ahn et al., 2006 [this issue of Molecular Cell]) describes a specific deacetylation/phosphorylation crosstalk at the histone H2B tall required for apoptosis induction in yeast, thus giving first insights into the poorly understood epigenetic regulation of cell death.