THIENO2,3-fTRIAZOLO1,5-a1,4DIAZEPINES AND THIENO2,3-f-TRIAZOLO1,5-a1,4OXAZEPINES FROM AZIDE CYCLOADDITION

摘要

Intramolecular dipolar cycloadditions between 2-methoxycarbonyl-3-thenylazide (3) and monosubstituted dipolarophiles bearing a triple carbon-carbon bond were exploited in a three step synthesis of the title compounds. The intramolecular cycloaddition of substituted thenylazide (11) was also carried out in the two-step synthesis of the thieno2,3-f1,2,3triazolo1,5-a-1,4 diazepine derivative (8).