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首页> 外文期刊>Multiple sclerosis: clinical and laboratory research >Spiroergometric and spirometric parameters in patients with multiple sclerosis: are there any links between these parameters and fatigue, depression, neurological impairment, disability, handicap and quality of life in multiple sclerosis?
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Spiroergometric and spirometric parameters in patients with multiple sclerosis: are there any links between these parameters and fatigue, depression, neurological impairment, disability, handicap and quality of life in multiple sclerosis?

机译：多发性硬化症患者的肺功能测定和肺活量测定参数：这些参数与多发性硬化症的疲劳，抑郁，神经功能障碍，残疾，残障和生活质量之间是否有任何联系？

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One-hundred and twelve patients with multiple sclerosis were selected as population-based sample and examined on impairment (Expanded Disability Status Scale), disability (Barthel Index), handicap (Environment Status Scale), the quality of life (Multiple Sclerosis Quality of Life), fatigue (Modified Fatigue Impact Scale), depression (Beck Depression Inventory Score), respiratory function (spirometric parameters on spirometry) and physical fitness (spiroergometric parameters on a bicycle ergometer). The aim of the study was to examine and analyse (descriptive statistics) spiroergometric and spirometric parameters in patients with multiple sclerosis. Firstly, we tested the hypothesis whether spiroergometric and spirometric parameters are decreased and whether there are any correlations between these parameters and measures of impairment, depression, disability, handicap and quality of life. Secondly, we tested the hypothesis whether there is any correlation between a possible deconditioning and fatigue, and between a possible respiratory dysfunction and fatigue in multiple sclerosis. It results from this study that many spiroergometric parameters in patients with multiple sclerosis are significantly lowered in comparison to the population norm. A link can be found between some spiroergometric parameters and neurological impairment, disability, handicap and quality of life. It is not possible to prove any correlation between spiroergometric parameters and depression. From the spirometric parameters, these are expiratory flows that are significantly lowered in MS patients. It is not possible to prove any correlation between spirometric parameters and fatigue, depression, neurological impairment, duration of the disease, disability, handicap and quality of life in multiple sclerosis.
机译：选择一百一十二名多发性硬化症患者作为基于人群的样本，并检查其损伤（扩展残疾状况量表），残疾（Barthel指数），残障（环境状况量表），生活质量（多发性硬化症生活质量） ），疲劳（修改后的疲劳影响量表），抑郁（贝克抑郁量表评分），呼吸功能（肺活量计上的肺活量参数）和身体健康状况（自行车测功机上的肺功量参数）。这项研究的目的是检查和分析（描述性统计）多发性硬化症患者的体电和肺活量参数。首先，我们检验了以下假设：气压测量和肺活量测定参数是否降低，以及这些参数与减损，抑郁，残疾，残障和生活质量的度量之间是否存在任何相关性。其次，我们检验了这一假设，即在多发性硬化症中，可能的失调与疲劳之间，以及可能的呼吸功能障碍与疲劳之间是否存在任何相关性。这项研究的结果是，与人群正常情况相比，多发性硬化症患者的许多人体测量参数显着降低。在一些人体计量学参数与神经功能障碍，残疾，残障和生活质量之间可以找到联系。不可能证明气压测量参数与抑郁之间有任何相关性。从肺活量参数来看，这些是呼气流量，在MS患者中明显降低。肺活量测定参数与多发性硬化症的疲劳，抑郁，神经功能障碍，疾病持续时间，残疾，残障和生活质量之间没有任何相关性。

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