Iodine-catalyzed C-H bond activation by selenium dioxide: synthesis of diindolylmethanes and di(3-indolyl)selanides

摘要

An efficient reaction protocol was developed for the synthesis of several diindolylmethane derivatives via the C-H bond activation of aryl methyl ketones by and indoles in the presence of catalytic amounts of at 80 using dioxane as solvent. Unexpectedly, an interesting class of di(3-indolyl)selenide compounds was isolated when the reaction was carried out at room temperature.