From the LiteratureCase Reports

摘要

A 55-year-old woman developed hepatitis while taking gluco-samine, soybean extract and lutein; she was subsequently found to have a mutation in an iron metabolism gene.In June 2005, the woman underwent an unrelated blood test, which identified liver function abnormalities. Her liver function deteriorated and, on 26 July 2005, she was hospitalized. Analyses identified marked elevation in levels of ALT (693 IU/L), AST (533 IU/L), total bilirubin (1.3 mg/dL), serum iron (198 |Xg/dL) and serum ferritin (983 ng/mL). Information from her family revealed that, following the development of cataracts in October 2004, she had started self-administering nonprescription supplements; she had been taking glucosamine, lutein and soybean extract [dosages not stated] for >6 months [duration not clearly stated] prior to her admission.