Centennial Perspective: Serotonin Receptors

摘要

When the senior author agreed to write a historical overview of serotonin (5-HT) receptors, she did so without much thought of the magnitude of such an undertaking. Having been introduced to 5-HT research in 1962 as a graduate student, a mere five years after Gaddum and Picarelli proposed the first classification of 5-HT receptors, Sanders-Bush was there at the beginning. But with fourteen 5-HT receptors now recognized, the task of a historical account seemed overwhelming, hence the solution was to choose four seminal papers that were considered landmarks, shaping the field.