A clutter removal method for the Doppler ultrasound signal based on a nonlinear diffusion equation

摘要

Strong clutter components produced by stationary and slow-moving tissue structures render the lower frequency part of the spectrogram useless and degrade the accuracy of clinical ultrasound indices. An adaptive method based on the nonlinear forward-and-backward diffusion equation (FAB-DE) is proposed to remove strong clutter components from the contaminated Doppler signal. The clutter signal is extracted first by the FAB-DE accurately, in which the nonlinear diffusion coefficient function of the FAB-DE locally adjusts according to signal features and the diffusion adaptively switches between forward and backward mode. The present method has been validated by simulated and realistic pulse wave Doppler signals, and compared with the conventional high pass filter and the matching pursuit method. The simulation results, including spectrogram, mean velocity error, standard deviation of mean velocity and signal-to-clutter ratio of a decontaminated signal, demonstrate that the present FAB-DE method can remove clutter sufficiently and retain more low blood components simultaneously as compared with the other two methods. Results of the realistic Doppler blood signal, including spectrogram and low-frequency part of the spectrum, support the conclusion drawn from simulation cases.