Damaged-bone remodeling theory: Thermodynamical approach

摘要

The bone remodeling process is generally viewed as bone material response to functional demands and muscle attachments by continual process of growth, reinforcement and resorption which occur in living situation. Everyday activities damage bone, and this damage is normally repaired in a continuous remodeling process. When an imbalance in this remodeling process occurs, bones may become more susceptible to fracture. An attempt to establish a relationship between induced microdamage and adaptive bone remodeling is proposed. A thermodynamic theoretical framework is provided as basis for a consistent formulation of bone remodeling involving a chemical reaction and mass transfer between two constituents in presence of microcracks.