HUISGEN CYCLOADDITION WITH ACETYLENE GAS BY USING AN AMPHIPHILIC SELF-ASSEMBLED POLYMERIC COPPER CATALYST

摘要

A copper-mediated Huisgen cycloaddition, aka the copper(I)-catalyzed alkyne-azide cycloaddition (CuAAC), of flammable acetylene gas and a variety of organic azides proceeded smoothly by using our amphiphilic self-assembled polymeric copper catalyst MPPI-Cu to give the corresponding triazoles in high yield. MPPI-Cu was readily reused without loss of catalytic activity. The XAFS and DFT calculation studies revealed the local structure near Cu atom of an active species MPPI-Cu(I).