Contra lateral lymph node recurrence in breast cancer: Regional event rather than distant metastatic disease. A systematic review of the literature

摘要

Aims: After treatment for breast cancer, some patients experience a contralateral lymph node recurrence (CLNR). Traditionally, contralateral nodes are considered a distant site. However, aberrant lymph drainage after previous surgery is common. This might indicate that CLNR is a regional event. This study aimed to review the literature to determine prognosis after CLNR.