Fermentative optimization of culture conditions for large scale production of engineered synthetic antimicrobial peptide using salt inducible E. coli GJ1158

摘要

Aim. The aim of this paper was to optimize the media composition, influence of components and culture conditions using one-factor-at-a-atime, statistical designs and batch and fed batch fermentation for the production of synthetic cationic antimicrobial peptide (synthetic cAMP) from salt inducible E. coli GJ1158.