Phase I/II study of docetaxel, cisplatin, and 5-fluorouracil combination chemoradiotherapy in patients with advanced esophageal cancer

Miyazaki Tatsuya; Sohda Makoto; Tanaka Naritaka; Suzuki Shigemasa; Ieta Keisuke; Sakai Makoto; Sano Akihiko; Yokobori Takehiko; Inose Takanori; Nakajima Masanobu; Fukuchi Minoru; Ojima Hitoshi; Kato Hiroyuki; Kuwano Hiroyuki

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Phase I/II study of docetaxel, cisplatin, and 5-fluorouracil combination chemoradiotherapy in patients with advanced esophageal cancer

机译：多西他赛，顺铂和5-氟尿嘧啶联合放化疗在晚期食管癌患者中的I / II期研究

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This phase I/II study was aimed to determine the recommended dose (RD) of docetaxel, cisplatin, and 5-fluorouracil as combination chemoradiotherapy (DCF-RT) for patients with esophageal cancer and to evaluate the efficacy and safety of this protocol.

机译：这项I / II期研究旨在确定多西他赛，顺铂和5-氟尿嘧啶作为食管癌患者联合放化疗的推荐剂量（RD），并评估该方案的疗效和安全性。

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来源
《Cancer chemotherapy and pharmacology.》 |2015年第3期|共7页
作者
Miyazaki Tatsuya; Sohda Makoto; Tanaka Naritaka; Suzuki Shigemasa; Ieta Keisuke; Sakai Makoto; Sano Akihiko; Yokobori Takehiko; Inose Takanori; Nakajima Masanobu; Fukuchi Minoru; Ojima Hitoshi; Kato Hiroyuki; Kuwano Hiroyuki;
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正文语种 eng
中图分类药理学;
关键词
Docetaxel; Cisplatin; 5-Fluorouracil; Chemoradiotherapy; Esophageal cancer;

机译：多西他赛;顺铂;5-氟尿嘧啶;放化疗;食道癌;

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专利

1. Phase I/II study of docetaxel, cisplatin, and 5-fluorouracil combination chemoradiotherapy in patients with advanced esophageal cancer [J] . Miyazaki Tatsuya, Sohda Makoto, Tanaka Naritaka, Cancer chemotherapy and pharmacology. . 2015,第3期

机译：多西他赛，顺铂和5-氟尿嘧啶联合放化疗在晚期食管癌患者中的I / II期研究
2. Randomized controlled phase II comparison study of concurrent chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil versus CCRT with cisplatin, 5-fluorouracil, methotrexate and leucovorin in patients with locally advanced squamous cell carcinoma of the head and neck [J] . Mamoru Tsukuda, Junichi Ishitoya, Hideki Matsuda, Cancer Chemotherapy and Pharmacology . 2010,第4期

机译：多西他赛，顺铂和5-氟尿嘧啶同时放化疗联合CCRT联合顺铂，5-氟尿嘧啶，甲氨蝶呤和亚叶酸的随机对照II期比较研究在局部晚期头颈部鳞状细胞癌患者中的应用
3. Randomized controlled phase II comparison study of concurrent chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil versus CCRT with cisplatin, 5-fluorouracil, methotrexate and leucovorin in patients with locally advanced squamous cell carcinoma of the head and neck. [J] . Tsukuda M, Ishitoya J, Matsuda H, Cancer chemotherapy and pharmacology. . 2010,第4期

机译：随机对照期同期对多西紫杉醇，顺铂和5氟尿嘧啶与顺铂，5-氟尿嘧啶，甲氨蝶呤和白草素患者的头部和颈部临床和颈部癌症的随机化学疗法对比研究。
4. Phase I/II clinical trials on the effect of weekly paclitaxel (wPTX) and wPTX containing combination regimens for advanced and metastatic gastric cancer -ECRIN group studies [C] . Sakamoto J, Kodera Y, Kobayashi M, International Gastric Cancer Congress . 2009

机译：I / II期临床试验关于每周紫杉醇（WPTX）和WPTX含有晚期和转移性胃癌组合方案的临床试验 - 分泌组研究
5. The effect of curcumin and tetrahydrocurcumin in combination with 5-fluorouracil on esophageal cancer cell lines. [D] . Pendleton, Emily G. 2015

机译：姜黄素和四氢姜黄素联合5-氟尿嘧啶对食管癌细胞系的作用。
6. First-line dose-dense chemotherapy with docetaxel cisplatin folinic acid and 5-fluorouracil (DCF) plus panitumumab in patients with locally advanced or metastatic cancer of the stomach or gastroesophageal junction: final results and biomarker analysis from an Italian oncology group for clinical research (GOIRC) phase II study [O] . Gianluca Tomasello, Nicola Valeri, Michele Ghidini, 2017

机译：多西紫杉醇顺铂亚叶酸和5-氟尿嘧啶（DCF）加上帕尼单抗的一线剂量密集化疗在胃或胃食管交界处局部晚期或转移性癌症的患者中：来自意大利肿瘤学小组的临床最终结果和生物标志物分析研究（GOIRC）第二阶段研究
7. Induction chemotherapy with docetaxel/cisplatin/5-fluorouracil followed by randomization to two cisplatin-based concomitant chemoradiotherapy schedules in patients with locally advanced head and neck cancer (CONDOR study) (Dutch Head and Neck Society 08-01): A randomized phase II study [O] . Driessen, C. M. L., de Boer, J. P., Gelderblom, H., 2016

机译：多西他赛/顺铂/ 5-氟尿嘧啶诱导化疗，然后随机分配至局部晚期头颈部癌患者的两种基于顺铂的同时放化疗方案（CONDOR研究）（荷兰头颈学会08-01）：II期随机研究

Phase I/II study of docetaxel, cisplatin, and 5-fluorouracil combination chemoradiotherapy in patients with advanced esophageal cancer

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