Enhancement of Confocal Fluorescence Images of Neutrophils by Magnetic Fields

摘要

Fluorescent images of human neutrophil cells were obtained from confocal microscopy with and without the application of a magnetic field. This novel approach of imaging is found to be very useful for detecting cell structures, and also to reveal the morphological details which were not seen in images obtained without a magnetic field. In this study, the presence of a magnetic field revealed the intracellular distribution of p22-phox, an important component of the NADPH oxidase protein complex. This innovation will open a window in the morphological and immunohistochemical investigation of cells which is so important for medical sciences and clinical applications.