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Optical microsystem design and fabrication for medical image magnification

机译:用于医学图像放大的光学微系统设计与制造

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摘要

Medical imaging is an important part of diagnosis. The procedure should provide valuable information for diagnosis and, at the same time, should be minimally invasive for the patient. Therefore, when performing endoscopic imaging, a system with reduced dimensions is crucial. The performance of imaging systems, used in several diagnosis endoscopic procedures, would highly benefit from the integration of an imaging magnification optical microsystem (IMOM) able to perform in vivo and real-time tissue microscopy. This paper proposes a miniaturized IMOM: its total length is 12.164 mm and has a lateral lens assembly of 3.894 mm. A microfabricated PDMS lens was included in the system, obtained by a hanging droplet approach, a very low-cost and effective method. A paraxial magnification of 4-14 times was achieved with a good performance in every optical analysis evaluated. A modulation transfer function around 38 % at 50 lp/mm was obtained and maximum distortion about 1.8 %.
机译:医学成像是诊断的重要部分。该程序应为诊断提供有价值的信息,同时应对患者进行微创。因此,在进行内窥镜成像时,减小尺寸的系统至关重要。用于多种诊断内窥镜检查程序中的成像系统的性能,将从能够执行体内和实时组织显微镜检查的成像放大光学微系统(IMOM)的集成中受益匪浅。本文提出了一种小型IMOM:其总长度为12.164毫米,侧面透镜组件为3.894毫米。系统中包括一个微细的PDMS透镜,该透镜是通过悬挂液滴法获得的,这是一种非常低成本且有效的方法。在每个评估的光学分析中,近轴放大率达到4-14倍,并具有良好的性能。在50 lp / mm处获得约38%的调制传递函数,最大失真约为1.8%。

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