Cyclization of 5-(2-chloroethoxy)-1,5-dihydro-2H-pyrrol-2-ones

摘要

The intramolecular cyclization of substituted 5-(2-chloroethoxy)- 1,5-dihydro-2H-pyrrol-2ones in the presence of lithium diisopropylamide hexamethylphosphoramide in tetrahydrofuran gave tetrahydropyrano [2,3-b]pyrrol-6(2H) -ones and 3,4-dihydro-2H-pyrrolo [2,1-b] [1,3] oxazin-6(8aH)-ones in moderate to good yields. [References: 9]